Pathophysiology

Heart Failure

Heart Failure

Heart failure occurs when the heart is unable to pump sufficient blood to meet the metabolic needs of tissues.

Left-Sided vs. Right-Sided

  • Left-sided: Dyspnea, crackles, cough, orthopnea
  • Right-sided: Peripheral edema, JVD, hepatomegaly
  • Both: Fatigue, activity intolerance, weight gain

Pharmacotherapy

  • ACE inhibitors/ARBs to decrease afterload
  • Loop diuretics (furosemide) to reduce fluid volume
  • Beta-blockers to decrease cardiac workload
  • Digoxin to improve contractility

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