Maternal-Newborn

Rho(D) Immune Globulin (RhoGAM)

Rho(D) Immune Globulin (RhoGAM)

A medication given to Rh-negative mothers to prevent the development of antibodies against Rh-positive fetal blood cells.

Administration Timing

  • At 28 weeks gestation for prophylaxis
  • Within 72 hours after birth if the infant is Rh-positive
  • After any invasive procedures like amniocentesis or trauma

Eligibility Criteria

  • Mother must be Rh-negative
  • Mother must not have been previously sensitized (negative antibody screen)
  • Infant must be Rh-positive

Nursing Considerations

  • It is a blood product; verify patient ID and orders
  • Observe for allergic reaction
  • Do not administer to an Rh-positive mother

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