Pharmacology

Warfarin Therapy

Warfarin Therapy

Warfarin is an oral anticoagulant that acts as a Vitamin K antagonist to prevent thromboembolic events.

Monitoring

  • Monitor PT/INR levels regularly; target INR is typically 2.0-3.0.
  • Vitamin K is the antidote for warfarin overdose.
  • Monitor for signs of bleeding: hematuria, epistaxis, gum bleeding, bruising.
  • Instruct patient to maintain consistent intake of Vitamin K-rich foods (leafy greens).

Patient Education

  • Use a soft-bristled toothbrush and electric razor.
  • Avoid NSAIDs and aspirin due to increased bleeding risk.
  • Notify provider before any dental or surgical procedures.

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