Introduction to Biochemistry

Mitochondrial Function

Mitochondrial Function

The mitochondria are the powerhouse of the cell, serving as the site for the Krebs cycle and oxidative phosphorylation.

ATP Production

  • Electron Transport Chain (ETC) requires oxygen as the final electron acceptor.
  • Oxidative phosphorylation generates the majority of cellular ATP.
  • Mitochondrial DNA is maternally inherited.

Clinical Correlation

  • Hypoxia leads to ATP depletion and cellular injury/death.
  • Mitochondrial toxins can cause metabolic crisis.

Like what you see?

Subscribe to unlock all 360 Study Cards and 15,000+ flashcards, track your progress, and study anywhere.