Introduction to Biochemistry
Enzyme Kinetics
Enzymes act as biological catalysts by lowering activation energy to increase reaction rates.
Factors Affecting Rate
- Substrate concentration: Reaction rate increases until enzyme saturation occurs.
- Temperature: Rates increase with heat until thermal denaturation occurs.
- pH: Each enzyme has an optimal pH range for peak activity.
Nursing Relevance
- Serum enzyme levels (e.g., CK-MB, Troponin) assist in diagnosing tissue injury.
- Enzyme inhibition is the mechanism of action for many medications like ACE inhibitors.
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