Pathophysiology

Hyperthyroidism (Thyroid Storm)

Hyperthyroidism (Thyroid Storm)

Hyperthyroidism is a state of hypermetabolism, with Thyroid Storm representing an acute, extreme manifestation of thyrotoxicosis.

Clinical Signs

  • Tachycardia and palpitations
  • Heat intolerance and diaphoresis
  • Weight loss despite increased appetite
  • Exophthalmos (Grave’s disease specific)

Management

  • Administer antithyroid meds (Methimazole/PTU)
  • Administer beta-blockers for cardiac symptoms
  • Cooling blankets to manage hyperthermia
  • Maintain a calm, quiet environment

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